tyrosinekinase相关论文
Angiogenesis has been demonstrated to be a basic prerequisite for sustainable growth and proliferation of tumor[1],the l......
STYK1 404 tyrosine residue mutation enhances STYK1 mediated PI3K signaling transductions and human b
STYK1(putative serine/threonine and tyrosine kinase)is a newly identified novel oncogene which belongs to the receptor p......
The combination of a novel Bruton tyrosine kinase (BTK)inhibitor PLS123 and mTOR inhibitor everolimu
目的： Mantle cell lymphoma (MCL) is an aggressive and incurable malignant lymphoma with a median survival of 5 years ......
FLT3 基因即FMS样酪氨酸激酶3(Fms-like tyrosine kinase 3)也称为胎肝激酶2(fetal liver kinase-2)或人干细胞激酶1(human stem c......
目的 探讨Fms样酪氨酸激酶3(FLT3)表达对评估急性髓系白血病(AML)预后的意义.方法 选取AML患者50例,其中核型正常的AML患者20例,核......
AIM: Many growth factors, such as epidermal growth factor(EGF), are associated with the carcinogenesis. EGF plays itsrol......
TO THE EDITORrnHepatocellular carcinoma (HCC) is thought to develop through a multistep process[1]. A long history of v......
AIM: To investigate the antineoplastic potency of the novel insulin-like growth factor 1 receptor (IGF-1R) tyrosine kina......
Prolonged exposure of colon cancer cells to the epidermal growth factor receptor inhibitor gefitinib
AIM: To analyze the biological effects of prolonged in vitro exposure of HT-29 and LoVo colon cancer cell lines to gefit......
Design,synthesis and biological evaluation of pyrazolo[3,4-d]pyridazinone derivatives as covalent FG
Fibroblast growth factor receptors(FGFRs)have emerged as promising targets for anticancer therapy.In this study,we synth......
Gene deficiency or pharmacological inhibition of PDCD4-mediated FGR signaling protects against acute
Recent studies have shown that programmed cell death 4(PDCD4)modulates distinct signal transduction pathways in differen......
Pancreatic cancer is the fourth most common cause ofcancer deaths worldwide. Although recent therapeuticdevelopments for......
EGFR抑制剂是抗肿瘤药物研究的热点,文章就近年来新合成的六元并五元环母核类EGFR酪氨酸激酶抑制剂进行综述总结,重点关注国内外已......
